Heterocyclic substituted bisarylurea derivatives

Details Heterocyclic substituted bisarylurea derivatives Heterocyclic substituted bisarylurea derivatives

2011-08-23

2011-08-23

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S340000, C514S395000, C544S279000, C546S272400, C548S255000

Reexamination Certificate

active

08003657

ABSTRACT:
The present invention relates to heterocyclic substituted bisarylurea derivatives of formula I, the use of the compounds of formula I as inhibitors of one or more kinases, the use of the compounds of formula I for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.

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West, Anthony R., Solid State Chemistry and its Applications, Wiley, New York, 1988, pp. 358 & 365.
Manley et al., Urea derivatives of STI571 as inhibitors of Bcr-Abl and PDGFR kinases, Bioorganic & Medicinal Chemistry Letters, vol. 14, Issue 23, pp. 5793-5797, (2004) .

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