Heterocyclic substituted 2-acylamino-5-thiazoles, their preparat

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514252, 514307, 514314, 514326, 514365, 514366, 514367, 514369, 514370, 514371, 514372, 514374, 514375, 514376, 514377, 514378, 514385, 544116, 544119, 544120, 544124, 544128, 544130, 544133, 544135, 544137, 544139, 544140, 544141, 544142, 544143, 544145, 544146, 544147, 544152, 544153, 544235, 544353, 544357, 544360, 544363, 544364, 544366, 544367, 544368, 544369, 544370, 544371, 544372, 544373, 544374, 544375, 544376, 544379, 546139, 546144, 546145, 546167, 548151, 548195, 548196, A61K 31495, A61K 3150, A

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053148894

ABSTRACT:
A 2-Acylaminothiazole of formula: ##STR1## in which R.sub.1 is H, an alkyl or a substituted alkyl; R.sub.IV is a cycloalkyl, an aromatic group such as phenyl or a heterocyclic group which are unsubstituted or substituted; R.sub.V is a substituted alkyl, a substituted carboxy such as an ester or an amide; or R.sub.IV and R.sub.V together represent a phenoxyalkylene group which may be substituted on the phenyl; and Z is a heterocyclic e.g. indolyl group; or a salt of compound (I).

REFERENCES:
Bras et al., Chem. Abst. 116-21039y (1991).
Nguyen Minh Thao et al, Chem. Abst. 112-115589x (1989).
Uhlendorf et al, Chem. Abst 110-231432y (1988).
Nguyen Minh Thao et al, Chem. Abst. 101-171158n (1984).
Bourdais, Chem. Abst. 78-136065t (1972).

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