Heterocyclic substituted 2-acylamino-5-thiazoles, their preparat

Details Heterocyclic substituted 2-acylamino-5-thiazoles, their preparat Heterocyclic substituted 2-acylamino-5-thiazoles, their preparat

1994-03-03

1995-01-10

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

546209, 548181, 548184, 548193, 548198, C07D27740

Patent

active

053807367

ABSTRACT:
Heterocyclic substituted 2-acylamino-5-thiazoles, their preparation and pharmaceutical compositions containing them.
A 2-Acylaminothiazole of formula: ##STR1## in which R.sub.1 is H, an alkyl or a substituted alkyl; R.sub.IV is a cycloalkyl, an aromatic group such as phenyl or a heterocyclic group which are unsubstituted or substituted; R.sub.V is a substituted alkyl, a substituted carboxy such as an ester or an amide; or R.sub.IV and R.sub.V together represent a phenoxyalkylene group which may be substituted on the phenyl; and Z is a heterocyclic e.g. indolyl group; or a salt of compound (I).

REFERENCES:
Bras et al., Chem. Abst., 116-21039y (1991).
Nguyen Minh Thao et al., Chem. Abst., 112-115589x (1989).
Uhlendorf et al., Chem. Abst., 110-231432y (1988).
Nguyen Minh Thao et al., Chem. Abst., 101-171158r (1984).
Bourdais, Chem. Abst., 78-136065t (1972).

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