Heterocyclic modulators of PKB

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C544S224000, C544S235000, C544S242000, C544S253000, C544S283000, C546S112000, C546S139000, C546S152000, C546S157000, C548S360100, C548S361100, C548S302700, C548S306400, C514S248000, C514S299000, C514S387000, C514S403000

Reexamination Certificate

active

07897619

ABSTRACT:
The invention relates to heterocyclic compounds of Formula I and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein.The invention also relates to the therapeutic use of such compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.

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