Heterocyclic fatty acid amides

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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544158, 544176, 26029385, 2604025, 260404, 260408, 26029386, 424244, 4242485, 424267, 424312, 424320, C07D29518

Patent

active

040628418

ABSTRACT:
Acetylthio amides and esters were prepared by the free radical addition of thiolacetic acid to the terminal and nonterminal double bonds of N-substituted fatty amides and fatty esters. The free radical additions of the thiolacetic acid to the unsaturated compounds were initiated by irradiation using cobalt-60. The process using irradiation with cobalt-60 was also used to bring about the addition of bromotrichloromethane to N-substituted fatty amides and fatty esters to produce halogen-containing amides and esters. These new sulfur or halogen-containing compounds were found to have antimicrobial activity and to possess properties making them useful as antimicrobial agents.

REFERENCES:
tatsuo et al., "Chem. Abstracts", vol. 55 (1961), pp. 7323i-7324.

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