Heterocyclic ether compounds useful in controlling neurotransmit

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514210, 514269, 514309, 514312, 514318, 514326, 514340, 514343, 514369, 548186, 548189, 546141, 546153, 546193, 546209, 5462681, 5462761, 546275, 546283, 544238, 544298, 544408, 544360, 544333, 544372, 544359, C07D40112, C07D40312, C07D41712, A61K 31505, A61K 3150, A61K 31495, A61K 31425

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active

059143282

ABSTRACT:
Novel heterocyclic ether compounds of the formula: ##STR1## wherein *, A,B, n, R.sup.1, R.sup.2 and X are specifically defined, or pharmaceutically-acceptable salts or prodrugs thereof, which are useful in selectively activating or inhibiting neurotransmitter release; to therapeutically-effective pharmaceutical compositions of these compounds; and to the use of said compositions to activate or inhibit neurotransmitter release in mammals.

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K. Tomioka et al., Stereoselective Reactions XIX. Asymmetric Dihydroxylation of Olefins by Employing Osmium Tetroxide-Chiral Amine Complexes, Chem. Pharm. Bull., 1990, 38:2133-5.
Abbott Labs, Chemical Abstract 122:187598 for WO 94/08992 (Apr. 28, 1994), With the Printout.
Burger, Medicinal Chemistry, 3rd Ed (1970), pp. 72-77.
Silverman, The Organic Chemistry of Drug Design and Drug Action, (1992), pp. 19-21.

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