Heterocyclic esters of benzopyrans

Details Heterocyclic esters of benzopyrans Heterocyclic esters of benzopyrans

1973-05-21

1976-03-02

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602472B, 26029358, 26032634, 2603453, 424246, 424248, 424267, 424274, 424283, C07D31178

Patent

active

039417824

ABSTRACT:
This invention relates to novel esters of benzopyrans represented by the formulae ##SPC1##
Wherein R and R' are hydrogen or C.sub.1 -C.sub.6 alkyl and when alkyl are on the same or different carbons; R.sub.1 is C.sub.1 -C.sub.6 alkyl; R.sub.2 is C.sub.1 -C.sub.20 alkyl, lowercycloalkyloweralkyl or lowercycloalkyl; n is an integer from 3 to 7, and particularly 3 to 5; Y is a straight or branched chain C.sub.1 -C.sub.8 alkylene; and R.sub.3 is ##EQU1## WHEREIN A IS AN INTEGER FROM 1 TO 4, B IS AN INTEGER FROM 1 TO 4, X is O,S, CH.sub.2 or NR.sub.4 and R.sub.4 is hydrogen C.sub.1 -C.sub.6 alkyl, and R.sub.5 is hydrogen or C.sub.1 -C.sub.6 alkyl; and the acid addition salts thereof. The compounds exhibit analgesic and central nervous system activity.

REFERENCES:
patent: 3654312 (1972-04-01), Pars et al.
patent: 3676462 (1972-07-01), Pars et al.

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