Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1972-12-04
1976-11-09
Todd, G. Thomas
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
260240R, 260240D, 260240K, 260243B, 2602472B, 260268TR, 26029358, 260295T, 424248, 424250, 424263, 424267, C07D49104
Patent
active
039911942
ABSTRACT:
Novel heterocyclic esters of benzopyranopyridines represented by the formula ##SPC1##
Wherein R.sub.1 is hydrogen, lower alkyl, lower alkanoyl, cycloalkyl-lower alkyl, cycloalkyl-lower alkanoyl, lower alkenyl, lower alkynyl, halo-loweralkenyl, phenyl-lower alkyl, phenyl-lower alkenyl or phenyl-lower alkynyl; R.sub.2 is lower alkyl; R.sub.3 is an alkyl having one to twenty carbon atoms or a cycloalkyl-lower alkyl, Y is a straight or branched chain alkylene having one to eight carbon atoms, and R.sub.4 is a group of the formula ##EQU1## a is an integer from 1 to 4, b is an integer from 1 to 4 and X is CH.sub.2, O, S or N--R.sub.5 with R.sub.5 being hydrogen or lower alkyl, with the limitation that when X is O, S or N--R.sub.5, a and b each must be 2 and R.sub.6 is hydrogen or a lower alkyl group bonded to a carbon in the ring; and the acid addition salts thereof.
REFERENCES:
patent: 3452046 (1969-06-01), Yale et al.
patent: 3509163 (1970-04-01), Brandstrom et al.
patent: 3514464 (1970-05-01), Pars et al.
patent: 3522260 (1970-07-01), Shulgin
patent: 3542789 (1970-11-01), Satzinger
patent: 3656906 (1972-04-01), Bullock
patent: 3728360 (1973-04-01), Pars et al.
patent: 3787424 (1974-01-01), Pars et al.
Buzas et al., Compt. Rend. 256, 1804-1806, (1963).
Harris Louis Selig
Pars Harry George
Razdan Raj Kumar
Sheehan John Clark
Sharps Associates
Todd G. Thomas
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