Heterocyclic derivatives for the treatment of cancer and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S269700

Reexamination Certificate

active

07153875

ABSTRACT:
The invention relates to certain heterocyclic compounds useful for the treatment of cancer and other diseases, having the Formula (I):wherein:(a) m is an integer 0 or 1;(b) R12is an alkyl, a substituted alkyl, a cycloalkyl, a substituted cycloalkyl, a heterocyclic, a substituted heterocyclic, a heteroaryl, a substituted heteroaryl, an aryl or a substituted aryl residue;(c) Ar3is an aryl, a substituted aryl, a heteroaryl or a substituted heteroaryl residue;(d) Ar4is an aryl, a substituted aryl, a heteroaryl or a substituted heteroaryl residue;(e) R5is hydrogen, hydroxy, alkyl or substituted alkyl;(f) ----- represents a bond present or absent; and(g) W, X, Y and Z are independently or together —C(O)—, C(S), S, O, or NH;or a pharmaceutically acceptable salt thereof.

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