Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-09-19
1987-04-14
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514235, 514237, 514252, 514255, 514929, A61K 3150, A61K 31495, A61K 31535
Patent
active
046579060
ABSTRACT:
This invention relates to 5-(phenyl)-2(1H)-pyrazinones substituted in the 4-position of the phenyl ring by an amino or acylamino group. These compounds has inotropic activity. One specific compound is 5-(4-acetamidophenyl)-2(1H)-pyrazinone.
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patent: 4514568 (1985-04-01), Coates
Sheradsky et al., J.C.S. Perkin I:1296-1299, (1977).
Ohta et al., Hukusokan Kagaku Toronkai Kuen Yoshishu 8th:84-88, (1975), (Chem. Abst. 84:164, 723Y).
Greene, ed., Protective Groups in Organic Synthesis, John Wiley and Sons, New York, 1981, pp. 222-249.
McOmie, ed., Protective Groups in Organic Chemistry, Plenum Press, New York, 1973, pp. 46-61.
Emmett John C.
Slater Robert A.
Warrington Brian H.
Daniel Mark R.
Lourie Alan D.
Robinson Douglas W.
Smith Kline & French Laboratories Ltd.
Williams Janice E.
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