Heterocyclic compounds as COX-2 inhibitors

Details Heterocyclic compounds as COX-2 inhibitors Heterocyclic compounds as COX-2 inhibitors

1997-03-04

1998-09-22

Grumbling, Matthew V.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514339, 514365, 548181, 5462704, 544253, C07D40306, C07D40314, A61K 31495, A61K 3144

Patent

active

058114254

ABSTRACT:
The present invention relates to COX-2 inhibitors of the formula: ##STR1## wherein, A=halogen, C.sub.1 -C.sub.6 alkyl, SR.sup.1 or OR.sup.1 ;

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patent: 4391814 (1983-07-01), Vorbruggen
patent: 4618617 (1986-10-01), Yamamoto
patent: 4963689 (1990-10-01), Nagel et al.
patent: 5143927 (1992-09-01), Boschelli et al.
patent: 5484940 (1996-01-01), Grant et al.
Chiarino et al; Synthesis and In Solution Behaviour of New 2-Substituted-4-Thiazolidinecarboxylic Acid Derivatives; J. Heterocyclic Chem., 26, 589 (1989).

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