Heterocyclic compounds as ccr2b antagonists

Details Heterocyclic compounds as ccr2b antagonists Heterocyclic compounds as ccr2b antagonists

2011-03-15

2011-03-15

Havlin, Robert (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S252110

Reexamination Certificate

active

07906645

ABSTRACT:
Compounds of formula (I) Q-L-W—C(═X)—Z—P wherein Q is an amine of the formula —N(R1)(R2); L is an alkyl or heterocyclyl-alkyl linker; W is a 6- or 7-membered aliphatic ring comprising ring atoms Y1and Y2which are linked to groups L and C(X) respectively and Y1and Y2are independently selected from N and C; X is O, N, N—CN or S; Z is NR3; P is an optionally substituted monocyclic or bicyclic aryl or heteroaryl group; and pharmaceutically acceptable salts or solvates thereof, are useful in the treatment of C-C chemokine mediated conditions.

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