Heterocyclic compounds and their preparation and use

Details Heterocyclic compounds and their preparation and use Heterocyclic compounds and their preparation and use

1995-05-25

1997-07-08

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142328, 514 80, 544115, 544337, 544344, A61K 31495, A61K 31675, C07D24138, C07F 96509

Patent

active

056461461

ABSTRACT:
The present invention relates to 9H-indeno[1,2-b]pyrazin-3(4H)-ones and 9H-indeno[1,2-b]pyrazine-2,3(1H,4H)-diones or tautomeric forms thereof which are useful in treating neurological and psychiatric diseases based on the antagonism of the glycine binding site on the NMDA receptor complex.

REFERENCES:
patent: 4889855 (1989-12-01), Jacobsen et al.
patent: 4912108 (1990-03-01), Jacobsen et al.
patent: 5026704 (1991-06-01), Honore et al.
patent: 5081123 (1992-01-01), Honore et al.
patent: 5153195 (1992-10-01), Honore et al.
patent: 5182279 (1993-01-01), Jorgensen et al.
Bergel et al, "Journal of Chemical Society", 1964, University College, (London), pp. 3973-3981.
A.W. Johnson et al, "Journal of Chemical Society", 1960, University College, (London), pp. 3412-3413.

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