Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-04-04
1998-02-24
Owens, Amelia Averill
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514437, 514454, 549 26, 549223, 548525, 548528, A61K 3140, A61K 3138, A61K 3135
Patent
active
057212600
ABSTRACT:
The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts therefor, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
REFERENCES:
Pavia et al., J. Med. Chem., vol. 35, pp. 4238-4248, (1992).
Falch et al., Drug Design & Delivery, vol. 4, pp. 205-215, (1989).
Andersen Henrik Sune
Andersen Knud Erik
Hohlweg Rolf
J.o slashed.rgensen Tine Krogh
Madsen Peter
Lambiris, Esq. Elias J.
Novo Nordisk A S
Owens Amelia Averill
Zelson Esq. Steve T.
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