Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-08-17
2000-05-23
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514296, 514297, 540479, 540522, 540587, 546102, 546103, A01N 4346, A61K 3144, C07D48700, C07D51300, C07D21900
Patent
active
060666323
ABSTRACT:
The present invention relates to novel N-substituted azaheterocyclic compounds of the general formula ##STR1## wherein X, Y, Z, R.sup.1, R.sup.2 and r are as defined in the detailed part of the present description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonising peptides, e.g. non-insulin-dependent diabetes mellitus (NIDDM) and ageing-associated obesity.
REFERENCES:
patent: 5595989 (1997-01-01), Andersen et al.
Andersen Knud Erik
Fischer Erik
Hohlweg Rolf
J.o slashed.rgensen Tine Krogh
Olsen Uffe Bang
Novo Nordisk A S
Rozek Carol E.
Shah Mukund J.
Truong Tamthom N.
Zelson Steve T.
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