Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-10-24
1999-06-29
Rotman, Alan L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
514338, 514450, 549349, C07D40512, A61K 3144
Patent
active
059170476
ABSTRACT:
The present invention relates to novel N-substituted amino alcohols, amino acids and acid derivatives thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
REFERENCES:
patent: 4965259 (1990-10-01), Rozsa et al.
Kalman, A., et al. Acta Biochim. Biophys. Hung., vol. 24, Nos. 1-2, pp. 143-158 (1989).
Andersen Knud Erik
Hohlweg Rolf
J.o slashed.rgensen Tine Krogh
Konigova Otylie
Kovandova Martina
Aulakh Charanjit S.
Lambiris Elias J.
Novo Nordisk A S
Rotman Alan L.
Rozek Carol E.
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