Heterocyclic compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544 46, A61K 3155, A61K 3154, A61K 31445, C07D41706, C07D40106

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active

06043239&

ABSTRACT:
The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.

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Andersen et al., J. Med. Chem., vol. 36, p. 1716-1725, 1993.
Nakanishi et al., J. Med. Chem., vol. 13, No. 4, pp. 644-648, 1979.

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