Heterocyclic compounds

Details Heterocyclic compounds Heterocyclic compounds

1988-02-16

1990-03-20

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514398, 514399, 514400, 5482622, 548335, 548341, 548342, C07D23358, C07D24908, A61K 3141, A61K 31415

Patent

active

049102125

ABSTRACT:
A heterocyclic compound of the formula I, as shown hereafter in these claims in which n is 0 or 1; A is a 1-4C alkylene radical which may optionally bear one or more 1-4C alkyl substituents; R.sup.1 and R.sup.2, which may be the same or different, are each a hydrogen or halogen atom, an amino, carbamoyl, cyano, hydroxy, nitro or sulphamoyl radical, a 1-6C alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylamino, alkylcarbamoyl or alkylsulphamoyl radical, a di(1-6C alkyl)-amino, di(1-6C alkyl)carbamoyl or di(1-6C alkyl)sulphamoyl radical, or a 2-7C alkoxycarbonyl radical; m is an integer of 1 to 5, R.sup.3 is a hydrogen or halogen atom or a 1-6C alkyl or halogenoalkyl radical; and R.sup.4 is a 5-membered aromatic ring heterocyclyl radical containing 2 or 3 nitrogen atoms, or a 6-membered aromatic ring heterocyclyl radical containing 1 or 2 nitrogen atoms, which heterocyclyl radical may bear a 1-6C alkyl substituent; and for those compounds which contain a basic nitrogen atom, the pharmaceutically acceptable acid addition salts thereof together with processes of manufacture and pharmaceutical and veterinary compositions thereof.

REFERENCES:
patent: 4503062 (1985-03-01), Gravestock
patent: 4659730 (1987-04-01), Hirsch et al.
patent: 4737508 (1988-04-01), Lovey et al.
patent: 4755526 (1988-07-01), Hirsch et al.
patent: 4757082 (1988-07-01), Hirsch et al.

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