Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-09-04
1999-10-26
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540468, A61K 31395, C07D27301
Patent
active
059729252
ABSTRACT:
The present invention relates to novel N-substituted amino alcohols, amino acids and acid derivatives thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
REFERENCES:
patent: 4229350 (1980-10-01), Rozsa et al.
patent: 4965259 (1990-10-01), Rozsa et al.
Kalman, A., et al. Acta Biochim. Biophys. Hung., vol. 24, No. 1-2, pp. 143-158 (1989).
Andersen Knud Erik
Hohlweg Rolf
J.o slashed.rgensen Tine Krogh
Konigova Otylie
Kovandova Martina
Aulakh Charanjit S.
Lambiris Elias
Novo Nordisk A S
Rotman Alan L.
Rozek Carol E.
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