Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-07-04
2006-07-04
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S112000, C544S114000
Reexamination Certificate
active
07071189
ABSTRACT:
The present invention relates to heterocyclic compounds represented by the formula I or pharmaceutically acceptable salts thereof and antitumor agents containing the heterocyclic compounds as effective components:wherein X represents nitrogen atom or CH; R1represents CHnF3-n(wherein n is 1 or 2), hydroxy C1–C6alkyl, NHR6[wherein R6represents hydrogen atom or COR (wherein R represents hydrogen atom, C1–C6alkyl or C1–C6alkoxy)]; R2represents morpholino (which may be substituted with one to four C1–C6alkyl), thiomorpholino, piperidino, pyrrolidinyl (which may be substituted with hydroxy C1–C6alkyl), oxazolidinyl (which may be substituted with one or two C1–C6alkyl) or tetrahydro-1,4-thiazin-1-oxo-4-yl; R3and R4each represent hydrogen atom or C1–C6alkyl; and R5represents hydrogen atom, amino or hydroxyl.
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Kawashima Seiichiro
Matsuno Toshiyuki
Sasahara Hiroya
Watanabe Tetsuo
Yaguchi Shinichi
Balasubramanian Venkataraman
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Zenyaku Kogyo Kabushiki Kaisha
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