Heterocyclic carboxylic acid amides and esters of azabicyclic co

Details Heterocyclic carboxylic acid amides and esters of azabicyclic co Heterocyclic carboxylic acid amides and esters of azabicyclic co

1992-03-26

1993-03-02

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546112, A61K 31435, C07D47108

Patent

active

051909537

ABSTRACT:
Novel 1-azabicyclo[3.2.1]octan-5-ylmethyl and 1-azabicyclo[3.3.1]nonan-5-ylmethyl amines and alcohols are coupled with aryl carboxylic acids to obtain compounds having the formula: ##STR1## wherein X is --O-- or --NH-- and n is 1 or 2 which are useful in increasing gastric motility, in preventing emesis and emesis caused by anticancer treatments, anxiety, certain arrhythmias, and disorders caused by serotonin imbalances.

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