Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-05-30
2006-05-30
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S131000, C548S132000
Reexamination Certificate
active
07053110
ABSTRACT:
Heterocyclic aromatic compounds are provided which are useful in stimulating endogenous production or release of growth hormone and in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.The heterocyclic aromatic compounds have the structureincluding pharmaceutically acceptable salts thereof and all stereoisomers thereof,wherein Xais heteroaryl, preferably, and R1, R1a, R6, Y, Xb, A, B, Z, R3, R4, R4a, R5and R5aare as defined herein.
REFERENCES:
patent: 3239345 (1966-03-01), Hodge et al.
patent: 4036979 (1977-07-01), Asato
patent: 4411890 (1983-10-01), Momany
patent: 5206235 (1993-04-01), Fisher et al.
patent: 5283241 (1994-02-01), Bochis et al.
patent: 5284841 (1994-02-01), Chu et al.
patent: 5310737 (1994-05-01), Fisher et al.
patent: 5317017 (1994-05-01), Ok et al.
patent: 5374721 (1994-12-01), Schoen et al.
patent: 5430144 (1995-07-01), Schoen et al.
patent: 5430150 (1995-07-01), Trova et al.
patent: 5434261 (1995-07-01), Schoen et al.
patent: 5438136 (1995-08-01), Devita et al.
patent: 5536716 (1996-07-01), Chen et al.
patent: 5545735 (1996-08-01), Bochis et al.
patent: 5578593 (1996-11-01), Chen et al.
patent: 5583130 (1996-12-01), Bochis et al.
patent: 5606054 (1997-02-01), Fisher et al.
patent: 5622973 (1997-04-01), Morriello et al.
patent: 5652235 (1997-07-01), Chen et al.
patent: 5663171 (1997-09-01), Chen et al.
patent: 5672596 (1997-09-01), Wyvratt et al.
patent: 5726307 (1998-03-01), Schoen et al.
patent: 6114310 (2000-09-01), Chamberland et al.
patent: WO 93/14072 (1993-07-01), None
patent: WO 94/193637 (1994-09-01), None
patent: WO 95/16675 (1995-06-01), None
patent: WO 96/05195 (1996-02-01), None
patent: WO 96/22997 (1996-08-01), None
patent: WO 97/24369 (1997-07-01), None
patent: WO 98/58948 (1998-12-01), None
patent: WO 99/64401 (1999-12-01), None
Nargund et al., “Growth Hormone Secretagogues” in: Ann. Reports Med. Chem. vol. 32 (1997).
J.S. Morley, et al. “Antibacterial Activity and Uptake intoEscherichia coliof Backbone-modified Analgues of Small Peptides”; Journal of General Microbiology (1983), 129, pp. 3701-3708.
Smissman et al., “Synthesis of Inhibitors of Bacterial Cell Wall Biogenesis. Analogs of D-Alanyl-D-alanine”, Journal of Medicinal Chemistry (1976) 19, pp. 165-167.
Maekawa et al., “Synthesis and Biological Activities of Benzimidazole Derivatives”; Agric. Biol. Chem. (1977) 41(5), pp. 811-818.
Hernandez Andres S.
Li Jun
Robl Jeffrey A.
Tino Joseph A.
Anderson Rebecca
Bristol--Myers Squibb Company
Duncan, Jr. Sammy G.
Saeed Kamal A.
LandOfFree
Heterocyclic aromatic compounds useful as growth hormone... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Heterocyclic aromatic compounds useful as growth hormone..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heterocyclic aromatic compounds useful as growth hormone... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3594831