Heterocyclic amino substituted heteroaryl fused pyridines; GABA

Details Heterocyclic amino substituted heteroaryl fused pyridines; GABA Heterocyclic amino substituted heteroaryl fused pyridines; GABA

1999-02-26

2000-12-26

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

5142338, 51425304, 514301, 544362, 546114, C07D41304, C07D24104, C07D47102, C07D51304, C07D51504

Patent

active

061662038

ABSTRACT:
Disclosed are compounds of the formula ##STR1## or the pharmaceutically acceptable non-toxic salts thereof wherein: n is an integer from 0 to 3;

REFERENCES:
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Chemical abstracts, vol. 124, No. 1, Jan. 1, 1996, abstract No. 8851c, Kataoka, M., et al., "Preparation of 4-piperazinylcycloalkanopyridine derivatives as psychotropics" p. 939.
Barnard et al., "International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: Classification on the basis of subunit structure and receptor function" Pharmacological Reviews, pp. 291-314 (1998).
Database CAPLUS on STN, AN 1989:553665, Jensen et al. New one-step synthesis of 2,4-bis(dialkylamino)quinolines and 4,6-bis(dialkylamino)thieno(2,3-b)pyridines, Chem. Scr., vol. 28, No. 4, pp. 435-437, 1988.
Eiden et al., Cycliization of acetamide acetals, Arch. Pharm., vol. 319, No. 4, pp. 347-354, 1986.

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