Heterocyclic amines having central nervous system activity

Details Heterocyclic amines having central nervous system activity Heterocyclic amines having central nervous system activity

2008-04-29

2008-04-29

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S162000

Reissue Patent

active

10117634

ABSTRACT:
Tricyclic nitrogen containing compounds, having anxiolytic and anti-depressant activity and central nervous system activity of the following structural formula:and pharmaceutically acceptable salts thereof wherein R1and R2are independently hydrogen, C1-6alkyl or R1and R2are joined to form pyrrolidiae, piperidine, morpholine or imidazole. X is OCH3, SO2R3, SO2CF3or CN where R3is C1-6alkyl or an Aryl; and Y is hydrogen, Cl, Br, F, CN, CONR1R2, CF3, OCH3, SO2NR1R2. These new compounds are suitable for treating anxiolytic disorder, schizophrenia, Parkinson's disease, anxiety, depression or as compounds for lowering blood pressure or treating migraine headaches in patients in need of such treatment.

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