Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1991-11-01
1994-01-18
Bernhardt, Emily
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
546 13, 548110, 548405, 424 11, C07F 502, A61K 3322, A61K 4300
Patent
active
052801195
ABSTRACT:
Heterocyclic amine-borane compounds of the formula: ##STR1## wherein: A is a heterocyclic amine moiety selected from the group consisting of piperidine, substituted piperidine, piperazine, substituted piperazine, imidazole, substituted imidazole, pyrazole, substituted pyrazole, pyrazine, substituted pyrazine, pyrrole, substituted pyrrole, pyrrolidine, substituted pyrrolidine, indole, substituted indole, indoline, substituted indoline, quinoline, substituted quinoline, isoquinoline, substituted isoquinoline, thiazole, substituted thiazole, oxazole, substituted oxazole, thiazolidine, and substituted thiazolidine, wherein substitution is at any or all substituent positions, and comprises substituents selected from the group consisting of alkyl (preferably C.sub.1 -C.sub.10 linear or branched alkyl), alkylaryl, aryl, aralkyl, nitro, alkoxy, hydroxy, cyano, thiol, and halo;
REFERENCES:
patent: 3341582 (1967-09-01), Stafiej et al.
patent: 3415776 (1968-12-01), White
patent: 4312989 (1982-01-01), Spielvogel et al.
patent: 5023513 (1991-06-01), Spielvogel et al.
patent: 5116980 (1992-05-01), Gabel
patent: 5143907 (1992-09-01), Spielvogel et al.
Hall et al., Chemical Abstracts, vol. 116, No. 143648 (1991) (Abstract for Biomed. Pharmacother. 45 p. 333, 1991).
Gyori et al., Chemical Abstracts, vol. 100, No. 60906 (1984).
Emri et al., Chemical Abstracts, vol. 100, No. 174884 (1984).
Gyoeri et al., Chemical Abstracts, vol. 89, No. 108910 (1978).
Hall et al., Biomedicine & Pharmacotherapy, vol. 45, pp. 333-341 (1991).
Hall Iris H.
Sood Anup
Spielvogel Bernard F.
Bernhardt Emily
Boron Biologicals Inc.
Hultquist Steven J.
LandOfFree
Heterocyclic amine-boranes, and method of inhibiting DNA topoiso does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Heterocyclic amine-boranes, and method of inhibiting DNA topoiso, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heterocyclic amine-boranes, and method of inhibiting DNA topoiso will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1137298