Heterocyclic alkyl 4-pyrimidones

Details Heterocyclic alkyl 4-pyrimidones Heterocyclic alkyl 4-pyrimidones

1979-02-16

1980-08-05

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544238, 544295, 544296, 544319, C07D40106

Patent

active

042163188

ABSTRACT:
The compounds are substituted isocytosines which are histamine H.sub.2 -antagonists. Two specific compounds of the present invention are 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(3-pyridylmethyl)-4-py rimidone and 2-[2-(3-bromo-2-pyridylmethylthio)-ethylamino]-5-(4-pyridylmethyl)-4-pyrim idone.

REFERENCES:
patent: 3932644 (1976-01-01), Durant et al.
patent: 4145546 (1979-03-01), Brown et al.
patent: 4154834 (1979-05-01), Brown et al.

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