Heterocyclic acridone inhibitors of IMPDH enzyme

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S255050, C514S256000, C514S293000, C544S105000, C544S333000, C544S405000, C544S060000, C544S126000, C544S361000, C544S250000, C546S081000, C540S575000

Reexamination Certificate

active

06916809

ABSTRACT:
Compounds having the formula (I),wherein R3is selected from H, OH and NH2; R30is selected from ═O and ═S; W is —C(═O)—, —S(═O)—, or —S(O)2—; or W may be —CH2— if X is —C(═O)—; X is selected from —CH2—, —N(R4)—, and —O—, except that when W is —CH2—, X is —C(═O)—; Y is a bond or —C(R40)(R45)—; Q is a linker; Z is optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl, or heterocyclyl; and X1, X2, X3, X4, X5, X6, X7, X8, X9, X10and X11are selected such a tricyclic heteroaryl ring system is formed as further defined in the specification.

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