Heterocycle substituted propenoic acid derivatives and pharmaceu

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514414, 5462781, 548527, 548517, 540521, A61K 3144, C07D40106

Patent

active

055631576

ABSTRACT:
The present invention is new 3-(heterocyclic)-propenoic acid derivatives and pharmaceutical compositions thereof. These new 3-(heterocyclic)-propenoic acid derivatives are useful as NMDA antagonist.

REFERENCES:
patent: 5106847 (1992-04-01), Salituro et al.
Salituro F.G. et al., Bioorganic & Medicinal Chem. Ltrs, vol. 1, No. 9, pp. 455-460, 1991.
Kemp, John A. et al., TiPS-Jan. (vol. 14).
Schelkun, R.M. et al., 33rd Nat'l Organic Chemistry Symposium Bozeman, MT -Jun. 1993 Abstract #B-73.
Thornber Chemical Society Reviews vol. 8, No. 4, 1979.

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