Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-02
1996-08-27
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514314, 546159, 546168, 546287, 546289, C07D21518, C07D21538, C07D21542, A61K 3147
Patent
active
055501354
ABSTRACT:
The present invention is concerned with antiretroviral (e.g. anti-HIV-1) compounds having the formula ##STR1## wherein R.sup.1 and R.sup.2 each independently are halo or methyl; R.sup.3 is hydrogen, halo, nitro or trifluoromethyl; R.sup.4 is trifluoromethyl or methylcarbonyl; or a radical --C(.dbd.X)--NR.sup.5 R.sup.6 wherein X is O or S, and R.sup.5 and R.sup.6 each independently are hydrogen or C.sub.1-4 alkyl; or a radical -Alk-R.sup.7, wherein Alk is C.sub.1-4 alkanediyl; and R.sup.7 is hydrogen or hydroxy;
REFERENCES:
patent: 4246429 (1981-01-01), Van Daele
Bosmans Jean-Paul R. M. A.
Janssen Marcel A. C.
Janssen Paul A. J.
Van Daele Georges H. P.
Verdonck Marc G. C.
Janssen Pharmaceutica N.V.
Metz Charles J.
Rotman Alan L.
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