Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2003-08-25
2009-02-24
Blanchard, David J. (Department: 1643)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S008100, C530S418000
Reexamination Certificate
active
07494969
ABSTRACT:
A method of treating cancer dependent on growth factor GHRH in warm-blooded animals in need thereof with an isolated protein extended forPilocarpus Heterophyllus.
REFERENCES:
patent: WO 95/16707 (1995-06-01), None
patent: WO 02/068461 (2002-09-01), None
Alster, D.K., Bowers, C.Y., Jaffe, P.J., Ho, P.J., and Barkan, A.L. The Growth Hormone (GH) Response to GH-Releasing Peptide (His-dTrp-Ala-dPhe-Lys-NH2), GH-Releasing Hormone, and Thyrotropin-Releasing Hormone in Acromegaly. 1993. Journal of Clinical Endocrinology and Metabolism, vol. 77 No. 3 pp. 842-845.
Ezzat, S., Ezrin, C., Yamashita, S., and Melmed, S. Recurrent Acromegaly Resulting from Ectopic Growth Hormone Gene Expression by a Metastatic Pancreatic Tumor. 1993. Cancer, vol. 71 No. 1 pp. 66-70.
Freda, P.U. Somatostatin Analogs in Acromegaly. 2002. Journal of Clinical Endocrinology and Metabolism, vol. 87 No. 7 pp. 3013-3018.
Jaffe, C.A., DeMott-Friberg, R., Frohman, L.A., and Barkan, A.L. Suppression of Growth Hormone (GH) Hypersecretion due to Ectopic GH-Releasing Hormone (GHRH) by a Selective GHRH Antagonist. 1997. Journal of Clinical Endocrinology and Metabolism, vol. 82 No. 2 pp. 634-637.
Saravanan, R.S. and Rose, J.K.C. A critical evaluation of sample extraction techniques for enhanced proteomic analysis of recalcitrant plant tissues. Proteomics, 2004. vol. 4, pp. 2522-2532.
Schally, Varga, and Engel. Antagonists of growth-hormone-releasing hormone: an emerging new therapy for cancer. Nature Clinical Practice Endocrinology and Metabolism. 2008. vol. 4, pp. 33-43.
Jaffe et al, “Suppression . . . GHRH Antagonist”, Journal of Clinical Endocrinology and Metabolism, New York, NY, US, vol. 82, No. 2, 1997 pp. 634-637.
Ferrandis Eric
Sohier Christine
Teng Beng Poon
Thurieau Christophe
Blanchard David J.
Gussow Anne M.
Muserliar Charles A.
Societe de Conseils de Recherches et d'Applications Scientifique
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