Heterobifunctional pan-selectin inhibitors

Details Heterobifunctional pan-selectin inhibitors Heterobifunctional pan-selectin inhibitors

2006-09-01

2010-06-01

Jiang, Shaojia Anna (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S016600, C536S018700, C536S123100, C536S123130

Reexamination Certificate

active

07728117

ABSTRACT:
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics alone or linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).

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