Heteroatom-containing tricyclic compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546 63, 546 92, 546112, 546 14, 548428, 548453, 548423, 548110, 514291, 514299, 514411, 514413, 514410, 514 63, A61K 31435, A61K 3140, C07D27301

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active

055146856

ABSTRACT:
The invention concerns the compounds of formulae ##STR1## wherein the substituents have various significances. They can be prepared by various methods, e.g. acylation, reduction, alkylation, etc. They are indicated for use as pharmaceuticals, in particular as immunosuppressant, antiproliferative and antiinflammatory agents.

REFERENCES:
patent: 5254562 (1993-10-01), Okuhara et al.
patent: 5260301 (1993-11-01), Nakanishi et al.
Official Gazette--Jan. 16, 1990 p. 1384, USP 4,894,366.
European Search Report, EP 93 81 0325 (Aug. 1993).

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