Heteroaryloxy 3-substituted propanamines as serotonin and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S443000, C514S469000, C548S491000, C549S051000, C549S467000

Reexamination Certificate

active

07037932

ABSTRACT:
There is provided a heretoaryloxy 3-substituted propanamine compound of formula (I): wherein A is selected from —O— and —S—; X is selected from phenyl optionally substituted with up to 5 substituents selected from halo, C1–C4alkyl and C1–C4alkoxy, and thienyl optionally substituted with up to 3 substituents selected from halo and C1–C4alkyl; Y is selected from benzothienyl, indolyl and benzofuranyl, optionally substituted with up to 5 substituents selected from halo, C1–C4alkyl, C1–C4alkoxy, nitro, acetyl and cyano; and when Y is indolyl it may be substituted or further substituted by an N-substituent selected from C1–C4alkyl; R1and R2are each independently H or C1–C4alkyl; and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 4956338 (1990-09-01), Rapp et al.
patent: 4970232 (1990-11-01), Jakobsen et al.
patent: 5023269 (1991-06-01), Robertson et al.
patent: 0 373 836 (1990-06-01), None
patent: 2 060 622 (1981-05-01), None
patent: WO 0061539 (2000-10-01), None
patent: WO 0228815 (2002-04-01), None
Jakobsen et al., STN International, HCAPLUS Database (2005), Columbus, OH, Accession No. 1989:614216.

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