Heteroaryl sulfonamides and CCR2

Details Heteroaryl sulfonamides and CCR2 Heteroaryl sulfonamides and CCR2

2006-07-14

2009-11-24

Desai, Rita J (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C544S224000, C514S248000, C514S280000

Reexamination Certificate

active

07622583

ABSTRACT:
Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.

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