Heteroaryl substituted tetrazole modulators of metabotrophic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S268400

Reexamination Certificate

active

10491613

ABSTRACT:
Tetrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.

REFERENCES:
CAOLD Accession No. CA55: 7397b, Hopff, Heinrich et al, “Isopropenylation.”

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