Heteroaryl substituted spirocyclic sulfamides for inhibition...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S126000

Reexamination Certificate

active

11366866

ABSTRACT:
Compounds of formula I are disclosed:in which X is a 5-membered heteroaryl ring and R is as defined herein. The compounds are inhibitors of the processing of APP by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.

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