Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-05-13
2008-05-13
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S340000, C514S365000, C514S422000, C546S268100, C548S146000, C548S373100, C548S518000
Reexamination Certificate
active
10499393
ABSTRACT:
Pyrrole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorder and panic, as well as in the treatment of pain, circadian rhythm disorders, and other diseases.
REFERENCES:
CAPLUS Accession No. 1995:441009, abstract of Oishi et al journal article, Chemical & Pharm. Bulletin (1994), vol. 42(11), pp. 2219-2224.
Abstract of: Reiman, E., et al., “Intramolecular Alkylation of Aromatic Compounds. Part XXXIV. Synthesis of (Pyridinyl) Indoles as Potential Precursors to Ergolines”, Pharmazie (2000) vol. 55, No. 12 pp. 907-912.
Cosford Nicholas D. P.
Huang Dehua
Smith Nicholas D.
Coppins Janet L.
Krovatin William
Merck & Co. , Inc.
Saeed Kamal A.
Thies J. Eric
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