Heteroaryl fused azapolycyclic compounds

Details Heteroaryl fused azapolycyclic compounds Heteroaryl fused azapolycyclic compounds

2004-07-12

2008-11-25

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S233000, C544S095000, C546S063000, C435S184000, C514S229500, C514S286000

Reexamination Certificate

active

07456177

ABSTRACT:
The present invention provides a compound having the structure of formula I:wherein R1is hydrogen, (C1–C6) alkyl, unconjugated (C3–C6) alkenyl, benzyl, YC(═O)(C1–C6) alkyl or —CH2CH2—O—(C1–C4) alkyl; X is CH2or CH2CH2; Y is (C2–C6) alkylene; Z is (CH2)m, CF2, or C(═O), where m is 0, 1 or 2; R2and R3are selected independently from hydrogen, halogen, —(C1–C6) alkyl optionally substituted with from 1 to 7 halogen atoms, and —O(C1–C6) alkyl optionally substituted with from 1 to 7 halogen atoms, or R2and R3each together with the atom to which it is connected independently form C(═O), S→O, S(═O)2, or N→O; andis a 5- to 7-membered monocyclic heteroaryl group selected from pyridinyl, pyridone, pyridazinyl, imidazolyl, pyrimidinyl, pyrazolyl, triazolyl, pyrazinyl, furyl, thienyl, isoxazolyl, thiazolyl, oxazolyl, isothiazolyl, pyrrolyl, cinnolinyl, triazinyl, oxadiazolyl, thiadiazolyl and furazanyl groups.

REFERENCES:
patent: 6462035 (2002-10-01), Coe

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