Heteroaryl dihydroindolones as kinase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S114000, C546S115000, C546S122000

Reexamination Certificate

active

07977351

ABSTRACT:
The present invention provides a compound represented by the formula:wherein the variables R1, b, R6, Y, Z, X, R and a are defined in the specification.Said compound may be used in a method for treating diseases related to unregulated tyrosine kinase signal transduction, wherein said disease is selected from the group consisting of cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, and metabolic diseases.

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