Heteroaryl derivatives of monocyclic beta-lactam antibiotics

Details Heteroaryl derivatives of monocyclic beta-lactam antibiotics Heteroaryl derivatives of monocyclic beta-lactam antibiotics

1992-09-08

1994-03-01

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

544337, 544354, 544355, 560160, 564443, C07D41714, C07D24144, A61K 31495

Patent

active

052909298

ABSTRACT:
Antibacterial activity is exhibited by novel compounds having the formula ##STR1## where R.sub.1, R.sub.2, and M are as defined herein and X is --(CH.sub.2).sub.n -- wherein n is 0, 1, 2, 3 or 4 or CR.sub.3 R.sub.4 wherein R.sub.3 and R.sub.4 are the same or different and each is hydrogen, --CH.sub.3 or --C.sub.2 H.sub.5 or R.sub.3 and R.sub.4 taken together with the carbon atom to which they are attached form a 3, 4, 5, 6 or 7-membered cycloalkyl ring.

REFERENCES:
patent: 3997535 (1976-12-01), Collins
patent: 4217453 (1980-08-01), Christensen et al.
patent: 4224336 (1980-09-01), Christensen et al.
patent: 4587047 (1986-05-01), Breuer et al.
patent: 4610824 (1986-09-01), Truner
patent: 4670553 (1987-06-01), Breuer et al.
patent: 4743685 (1988-05-01), Breuer et al.
patent: 4772693 (1988-09-01), Breuer
patent: 4775670 (1988-10-01), Sykes et al.
patent: 4904775 (1990-02-01), Sundeen et al.
patent: 4959470 (1990-09-01), Treuner
patent: 5030724 (1991-07-01), Sundeen
patent: 5037983 (1991-08-01), Sundeen
Mochida et al.; Aminothiazolylglycyl Derivatives of Carbacephem Antibiotics, Feb. 1987, pp. 182-189, Journal of Antibiotics.
Mochida et al.; Aminothiazolylglycol Derivatives of Carbonacephems, Jan. 1987, pp. 14-21, Journal of Antibiotics.
Z. Budesinsky et al.; 6,7-Dialkoxychinoazlin-Derivatives, Collection Czechoslov. Chem. Commun., vol. 36, 1971, pp. 2527-2539.

Affiliated with

Also associated with

Rating

Heteroaryl derivatives of monocyclic beta-lactam antibiotics does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heteroaryl derivatives of monocyclic beta-lactam antibiotics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heteroaryl derivatives of monocyclic beta-lactam antibiotics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-578906