Heteroaryl derivates, their preparation and use

Details Heteroaryl derivates, their preparation and use Heteroaryl derivates, their preparation and use

2008-07-01

2008-07-01

Bernhardt, Emily (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252200, C514S253100, C544S105000, C544S295000, C544S364000, C544S318000, C544S333000, C546S194000, C546S256000, C540S575000, C540S597000, C540S598000, C540S599000, C540S600000

Reexamination Certificate

active

11758511

ABSTRACT:
A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis

REFERENCES:
patent: 5225409 (1993-07-01), Taverne et al.
patent: 2006/0258678 (2006-11-01), Rottlander et al.
Jones et al, Pharmacology, Biochem and Behav 2002, vol. 71, p. 555-568.
Robichaud et al, Annual Reports in Medicinal Chemistry 2000, vol. 36, p. 11-20.
TenBrink et al., J Med Chem 1996, vol. 39, p. 2435-2437.
Van Steen, B. J. “Structure activity relationship studies on 5-HT1A receptor ligands. 2. Heterocyclic Phenylpiperazines with N4-aralkylsubstituents” J. Med Chem 1994, vol. 37, p. 2761-2773.

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