Heteroaryl coumarins as inhibitors of leukotriene biosynthesis

Details Heteroaryl coumarins as inhibitors of leukotriene biosynthesis Heteroaryl coumarins as inhibitors of leukotriene biosynthesis

1993-06-23

1995-06-13

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514365, 514369, 514443, 514457, 546269, 548182, 548203, 549 60, 549283, A61K 3144, C07C31102

Patent

active

054243203

ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

REFERENCES:
patent: 5227399 (1993-07-01), Young et al.

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