Heteroaryl amines as novel acetylcholinesterase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546214, A61K 31445, C07D40506

Patent

active

059655747

ABSTRACT:
Compounds of the formula ##STR1## wherein ring A, ring B, ring D, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.11, R.sup.12, R.sup.13, E, G, X and P are as defined below. The compounds of formula I are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzheimer's disease.

REFERENCES:
patent: 2652399 (1953-09-01), Clinton
patent: 5273974 (1993-12-01), Goto
Wilbraham et al. "Organic and biological chemistry" Southern Ill. Univ. pp. 268-269, 1985.

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