Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-10-24
2000-09-26
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514321, 514323, 514324, 546196, 546197, 546198, 546199, 546201, 546202, A61K 31445, C07D27762, C07D41706
Patent
active
061243213
ABSTRACT:
Compounds of the formula ##STR1## wherein ring A, ring B, ring D, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6,R.sup.11, R.sup.12, R.sup.13, E, G, X and P are as defined below. The compounds of formula I are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzheimer's disease.
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Djuric et al., "Chemoselective Reductions of 2-Acyl-1H-indole-3-carboxaldehydes", J. Heterocyclic Chem., 22, 1425 (1985).
Chen Yuhpyng Liang
Nagel Arthur Adam
Chang Ceila
Ginsburg Paul H.
Jacobs Seth H.
Pfizer Inc
Richardson Peter C.
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