Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-03-08
2000-12-26
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514365, 514326, 546337, 546209, 548204, C07D21330, A61K 3144
Patent
active
061660523
ABSTRACT:
The present invention provides compounds that block calcium channels having the Formula I shown below. ##STR1## The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, asthma, amyotropic lateral sclerosis, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.
REFERENCES:
patent: 5232929 (1993-08-01), Desai
patent: 5332817 (1994-07-01), Desai et al.
patent: 5420297 (1995-05-01), Matsuo et al.
CA 127:51005, Horwell et al., 1997.
CA 120:45970, Woodruff, 1994.
CA 119:117788, Boden et al., 1997.
Hu Lain-Yen
Rafferty Michael Francis
Ryder Todd Robert
Sercel Anthony Denver
Song Yuntao
Ashbrook Charles W.
Fan Jane
Warner-Lambert & Company
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