Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-07-12
1994-10-11
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544260, 544279, 514258, A61K 31505
Patent
active
053547519
ABSTRACT:
There is disclosed certain heteroaroyl 10-deazaaminopterin and 5, 10 and 8, 10 di deazaminopterin compounds and their use for treatment of rheumatoid arthritis and related diseases and preparative process.
Also disclosed are 10 alkenyl-(and alkynyl) 10-deazaminopterins also disclosed for treatment of rheumatoid arthritis and for leukemia and ascites tumors and preparative process.
REFERENCES:
patent: 4369319 (1983-01-01), DeGraw et al.
patent: 4433147 (1984-02-01), DeGraw
patent: 4988813 (1991-01-01), Taylor et al.
patent: 5026851 (1991-06-01), Taylor et al.
patent: 5030634 (1991-07-01), Krumdieck et al.
patent: 5260296 (1993-11-01), Nair et al.
Washington Post, Apr. 16, 1992, p. A-14.
Colwell William T.
DeGraw Joseph I.
Piper James R.
Sirotnak Francis M.
Smith R. Lane
Daus Donald G.
Dolezalova Hana
SRI - International
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