Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-01-05
2008-09-30
Desai, Rita (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S314000
Reexamination Certificate
active
07429665
ABSTRACT:
The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.
REFERENCES:
patent: 4681940 (1987-07-01), Musser et al.
patent: 4876346 (1989-10-01), Musser et al.
patent: 5500427 (1996-03-01), Kubo et al.
patent: 5693652 (1997-12-01), Takase et al.
patent: 5843958 (1998-12-01), Ferro et al.
patent: 7250518 (2007-07-01), Magee et al.
patent: 2006/0111368 (2006-05-01), Osakada et al.
patent: WO 93/16071 (1993-08-01), None
patent: WO03/000269 (2003-01-01), None
patent: WO03/014115 (2003-02-01), None
patent: WO03/093499 (2003-11-01), None
patent: WO 2005/019211 (2005-03-01), None
patent: WO2005/120514 (2005-12-01), None
Musser, John H.; Kubrak, Dennis M.; Bender, Reinhold H. W.; Kreft, Anthony F.; Nielsen, Susan T.; Lefer, Allan M.; Chang, Joseph; Lewis, Alan J.; Hand, James M. Wyeth Lab., Inc., Philadelphia, PA, 19104, USA “Phenylephrine derivatives as leukotriene D4 antagonists” Journal of Medicinal Chemistry (1987), 30(11), 2087-93 CODEN: JMCMAR; ISSN: 0022-2623.
Victor Segarra, Phosphodiesterase inhibitory properties of losartin. Design and synthesis of new lead compounds, Bioorganic & Medicinal Chemistry Letters (1998), vol. 8, No. 5, pp. 505-510.
Helal Christopher J.
Hoover Dennis J.
Humphrey John M.
Verhoest Patrick R.
Desai Rita
Mabry John
Pfizer Inc
Smolizza Christian M.
Zelson Steve T.
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