Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1983-10-11
1985-07-09
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546201, 546208, 514326, C07D40112, A61K 31455
Patent
active
045282935
ABSTRACT:
Compounds of the following formula (I): ##STR1## wherein Alk is a straight or branched chain alkylene of about 1 to 12 carbons and R.sup.1 is a heterocyclic ring system, have been found to possess potent antisecretory activity and are thus useful in the treatment of hyperacidity.
REFERENCES:
patent: 4251655 (1981-02-01), Scott et al.
patent: 4370335 (1983-01-01), Scott
Castro, A. J. et al, "Alylation Reactions of the Pyrrole Grignard Reagent", J. Org. Chem., vol. 30 (1965) pp. 344-350.
Elming, N. et al, "Preparation of Pyrroles from Furans", Acta Chim. Scand., vol. 6 (1952) pp. 867-874.
Bjorkman Dale A.
Jiles Henry R.
Levy David J.
McNeilab Inc.
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