Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-11-24
1988-03-01
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514461, 514473, 514445, 514447, 514448, 549 65, 549 68, 549 75, 549479, 549480, 549491, A61K 3134, A61K 3138, C07D33306, C07D30736
Patent
active
047286660
ABSTRACT:
Heterocyclic acetylenes of the formula (I): ##STR1## wherein Y and R.sup.1 are substituents such as hydrogen, alkyl, alkoxy, chloro or fluoro, m is 0-2, R.sup.2 is branched alkyl and Het is an aromatic heterocycle. The acetylenes are useful in treating hypertension and/or angina.
REFERENCES:
patent: 3590084 (1971-06-01), Peperkamp et al.
patent: 3914432 (1975-10-01), Koppe et al.
patent: 3959338 (1976-05-01), Koppe et al.
patent: 4010158 (1977-03-01), Koppe et al.
patent: 4412856 (1983-11-01), Brunner et al.
"Linked Aryl Aryloxypropanolamines as a New Class of Lipid Catabolic Agents", Michael T. Cox et al., J. of Med. Chem., 1978, vol. 21, No. 2, pp. 182-188.
"2-(Isoxazolyethenyl)phenoxypropanolamines: A New Class of .beta.-Receptor Antagonists with Antihypertensive Activity", Franke et al., 1981 American Chemical Society.
Jiles Henry R.
Levy David J.
McNeilab Inc.
Richter J.
LandOfFree
Heteroaromatic acetylenes useful as antihypertensive agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Heteroaromatic acetylenes useful as antihypertensive agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heteroaromatic acetylenes useful as antihypertensive agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-998214