Hetero-aromatic ring substituted phenyloxazolidinone antimicrobi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548232, C07D41310, A61K 31422

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active

061243345

ABSTRACT:
A hetero-aromatic (Q) substituted phenyloxazolidinone antimicrobial of Formula I ##STR1## wherein Q is a 5-member hetero-aromatic having from one to four nitrogen atoms or alternatively a benzoannulated 5-member hetero-aromatic having from one to four nitrogen atoms where R.sup.1 is independentlyl H, OCH.sub.3, F, or Cl; and R.sup.2 is hydrogen, C.sub.1 -C.sub.8 alkyl (optionally substituted with one or more of F, Cl, hydroxy, C.sub.1 -C.sub.8 alkoxy, C.sub.1 -C.sub.8 acyloxy), C.sub.3 -C.sub.6 cycloalkyl, amino, C.sub.1 -C.sub.8 alkylamino, C.sub.1 -C.sub.8 dialkylamino, C.sub.1 -C.sub.8 alkoxy.

REFERENCES:
patent: 5684023 (1997-11-01), Riedl et al.
patent: 5698574 (1997-12-01), Riedl et al.
patent: 5883093 (1999-03-01), Hutchinson et al.
patent: 5910504 (1999-06-01), Hutchinson

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